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Epclusa is a prescription medication that is a combination of sofosbuvir and velpatasvir is used for the treatment of chronic (long-lasting) hepatitis C, a viral infection of the liver.


Generic Name: sofosbuvir and velpatasvir (soe FOS bue vir and vel PAT as vir)
Brand Names: Epclusa

What is Epclusa?

Epclusa is an antiviral medication that contains sofosbuvir and velpatasvir used in the prevention of the hepatitis C virus (HCV) from multiplying in your body in Adults and children of 6 years and above age.

Uses of Epclusa

Epclusa used in treatment and prevention of:

  • Hepatitis c.
  • Liver cirrhosis (with the comb to other medication)

Side effects of Epclusa

Some common side effects of Epclusa

  • Tiredness.
  • Headache.
  • Nausea.
  • Diarrhea.
  • Difficulty sleeping.

Consult your doctor immediately if any side effects occur, worsen, persist or any serious side effects occur.


  • Make sure you are not allergic to Epclusa.
  • Tell your doctor about your medical history.
  • Before going under surgery tell your doctor about the medication.
  • Before any vaccination, discuss with your doctor about your medication.
  • In pregnancy, Epclusa is not allowed.
  • Breastfeeding not allowed.


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