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Jakafi is a cancer medication that is used in the treatment of certain bone marrow disorders (myelofibrosis, polycythemia vera).

What is Jakafi?

Generic: Ruxolitinib

Classes: Hematologics, Kinase Inhibitors; Antineoplastics, JAK Inhibitors

Jakafi (ruxolitinib) blocks certain enzymes in the body that affect blood cell production. Jakafi is used in the treatment of myelofibrosis or polycythemia vera, which are bone marrow disorders that affect your body’s ability to produce blood cells.

Uses of Jakafi

  • Myelofibrosis.
  • Polycythemia vera.
  • Acute graft versus host disease (GVHD).

Side effects of Jakafi

  • Dizziness.
  • Diarrhea.
  • Headache.
  • Weight gain.
  • Gas may occur.

If any of these effects persist or worsen or any serious side effects, consult your doctor promptly.


  • Make sure you are not allergic to Jakafi.
  • Tell your doctor about your medical history.
  • Before going under surgery tell your doctor about the medication.
  • Before any vaccination, discuss with your doctor about your medication.
  • In pregnancy, Jakafi injection is not allowed.
  • Breastfeeding not allowed.


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